HEDS is part of the School of Health and Related Research (ScHARR) at the University of Sheffield. We undertake research, teaching, training and consultancy on all aspects of health related decision science, with a particular emphasis on health economics, HTA and evidence synthesis.

Thursday, 18 January 2018

Call for papers - PROMS Research Conference

The PROMS Research Conference will be hosted by the Centre for Patient Reported Outcomes Research at the University of Birmingham, UK on 20th June 2018.
Abstract submission is open. They welcome oral and poster abstracts from clinicians, researchers, patient partners, industry, SMEs and others working in the field. Professor John Brazier (HEDS, YH CLAHRC) is part of the organising committee.

Abstract Guidelines
All abstracts should be submitted via the abstract submission website. Abstract submission will close on Wednesday 28th February 2018.
Abstracts should be written in plain text and be a maximum of 300 words. Tables and images are not allowed in the abstract.

Image of Great Hall, Aston Webb, University of Birmingham
Conference venue © University of Birmingham 
Themes for this year:
Minimising PROs waste – in Research and beyond
Pushing the boundaries of patient & public involvement in PROs research
Digital capture of PROs
Cutting edge methods
We are open to receive other relevant work in the field, including clinical submissions.

Submitting authors can amend abstracts until the close date. Authors will be notified of abstract acceptance during week commencing 9th April. All correspondence regarding the abstracts will be sent to the submitting author. Please note that presenters of abstracts are not automatically registered for the conference.

Wednesday, 17 January 2018

December’s CEAs, systematic reviews and epidemiological models in LMICs

To help us keep on top of current research in low and middle-income countries, we are running a monthly search of research that is aligned to our core research interests.  It's a simple search strategy, with those published last month that are most aligned to our interests listed below.  The full list of articles is kept in our "Searches archive" in the right-hand column.
  • Gu S, Wang X, Qiao Q, Gao W, Wang J, Dong H. Cost-effectiveness of exenatide twice daily vs insulin glargine as add-on therapy to oral antidiabetic agents in patients with type 2 diabetes in China. Diabetes, obesity & metabolism. 2017;19(12):1688-97.
  • Lasalvia P, Baquero L, Otalora-Esteban M, Castaneda-Cardona C, Rosselli D. Cost Effectiveness of Dulaglutide Compared with Liraglutide and Glargine in Type 2 Diabetes Mellitus Patients in Colombia. Value in health regional issues. 2017;14:35-40.
  • Loganathan T, Ng CW, Lee WS, Hutubessy RCW, Verguet S, Jit M. Thresholds for decision-making: informing the cost-effectiveness and affordability of rotavirus vaccines in Malaysia. Health policy and planning. 2017.

Tuesday, 16 January 2018

NHS England consultations…

…on several Specialised Services clinical commissioning policies are open.  These proposals are based on a ‘rapid HTA process’ which was parly informed by work in HEDS.  The policies are:
  • Specialised Services clinical commissioning policy: Hyperbaric Oxygen Therapy for Carbon Monoxide Poisoning
  • Specialised Services clinical commissioning policy: Hyperbaric Oxygen Therapy for Decompression Illness/Gas Embolism
  • Specialised Services clinical commissioning policy: Anakinra to treat periodic fevers and autoinflammatory diseases (all ages)
  • Specialised Services clinical commissioning policy: Hyperbaric Oxygen Therapy for soft tissue radiation damage in patients with a history of pelvic irradiation for malignant disease
  • Specialised Services clinical commissioning policy: Anakinra/Tocilizumab for the treatment Adult Onset Still’s Disease refractory to second-line therapy (adults)
  • Adult Onset Still’s Disease refractory to methotrexate and corticosteroids. Related documents Anakinra/Tocilizumab... More
  • Specialised Services clinical commissioning policy: Deep Brain Stimulation for Refractory Tourette Syndrome in adults
  • Specialised Services clinical commissioning policy: Hyperbaric Oxygen Therapy for Malignant Otitis Externa
More details here

Monday, 15 January 2018

Website of the month - HTA News Portal

Yes, it’s a new feature….every month we pick out a website that we’ve found interesting.  This month it’s a new HTA news portal developed by Paul Mattheneus:

Mattheneus HTA Global HTA News Portal website

Thursday, 11 January 2018

December’s CEAs.....

Our quick search for CEA’s published in December uncovered 56 articles.   In the right-hand column of this blog is a CEA Archive, which includes our CEA search results by month.  Below are those in our areas of interest.
  • Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis. BMJ (Clinical research ed). 2017;359:j5631.
  • Dawoud D, Fenu E, Higgins B, Wonderling D, Amiel SA. Basal Insulin Regimens for Adults with Type 1 Diabetes Mellitus: A Cost-Utility Analysis. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2017;20(10):1279-87.
  • Jendle J, Ericsson A, Hunt B, Valentine WJ, Pollock RF. Achieving Good Glycemic Control Early After Onset of Diabetes: A Cost-Effectiveness Analysis in Patients with Type 1 Diabetes in Sweden. Diabetes therapy : research, treatment and education of diabetes and related disorders. 2017.
  • Klijn SL, van den Reek J, van de Wetering G, van der Kolk A, de Jong E, Kievit W. Biologic treatment sequences for plaque psoriasis: a cost-utility analysis based on 10 years of Dutch real-world evidence from BioCAPTURE. The British journal of dermatology. 2017.

Tuesday, 9 January 2018

Job Vacancy: Research Associate/Fellow in Health Economics & Decision Modelling

HEDS are advertising for a new Research Associate/Fellow in Health Economics & Decision Modelling. 

Closing date: 07.02.2018
Post ref: UOS018118

More details about the post and the application form can be viewed here: http://bit.ly/2D7PYWM

Image of the word Jobs
CC BY 2.0 Aaaarrrrgggghhhh!

Friday, 5 January 2018

Latest Publications from HEDS in December

Our regular monthly trawl for new publications from HEDS in collaboration with colleagues in ScHARR and further afield has reaped a tremendous amount of fresh research. Many of these are currently in press, so you can find much of our work in its open access form via our institutional repository. Tuck in here.   

Image of Journal of Clinical Epidemiology Journal
© Elsevier            
       Cargo, M., Harris, J., Pantoja, T., Booth, A., Harden, A., Hannes, K., Thomas, J., Flemming, K., Garside, R., Noyes, J., 2017. Cochrane Qualitative and Implementation Methods Group Guidance Paper 3: Methods for Assessing Evidence on Intervention Implementation. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.11.028

       Carlton, J., Griffiths, H., Mazzone, P., n.d. BIOS Screening Audit report 2015-2016. doi:10.15131/shef.data.5532910

       Comans, T.A., Nguyen, K.H., Mulhern, B., Corlis, M., Li, L., Welch, A., Kurrle, S., Rowen, D.L., Moyle, W., Kularatna, S., Ratcliffe, J., n.d. Developing a dementia-specific preference-based quality of life measure (AD-5D) in Australia: Valuation study protocol. BMJ Open.

Flemming, K., Booth, A., Hannes, K., Cargo, M., Noyes, J., 2017. Cochrane Qualitative and Implementation Methods Group Guidance Paper 5: Reporting guidelines for qualitative, implementation and process evaluation evidence syntheses. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.10.022

Harden, A., Thomas, J., Cargo, M., Harris, J., Pantoja, T., Flemming, K., Booth, A., Garside, R., Hannes, K., Noyes, J., 2017. Cochrane Qualitative and Implementation Methods Group Guidance Paper 4: Methods for integrating qualitative and implementation evidence within intervention effectiveness reviews. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.11.029

Harris, J.L., Booth, A., Cargo, M., Hannes, K., Harden, A., Flemming, K., Garside, R., Pantoja, T., Thomas, J., Noyes, J., 2017. Cochrane Qualitative and Implementation Methods Group Guidance series - paper 6: Methods for question formulation, searching and protocol development for qualitative evidence synthesis. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.10.023
The Stata Journal front cover
© StataCorp

Hernandez, M., pudney, S., n.d. EQ5DMAP: a command for mapping between EQ-5D-3L and EQ-5D-5L. Stata Journal.

Latimer, N.R., White, I.R., Abrams, K.R., Sieburt, U., 2017. Causal inference for long-term survival in randomised trials with treatment switching: Should re-censoring be applied when estimating counterfactual survival times?

Martin, N.H., Ibrahim, F., Tom, B., Galloway, J., Wailoo, A., Tosh, J., Lempp, H., Prothero, L., Georgopoulou, S., Sturt, J., Scott, D.L., Jenner, R., Neatrour, I., Baggott, R., Kingsley, G., Zhong, Y., Mian, A., 2017. Does intensive management improve remission rates in patients with intermediate rheumatoid arthritis? (the TITRATE trial): Study protocol for a randomised controlled trial. Trials 18. doi:10.1186/s13063-017-2330-8

Noyes, J., Booth, A., Cargo, M., Flemming, K., Garside, R., Hannes, K., Harden, A., Harris, J., Lewin, S., Pantoja, T., Thomas, J., 2017a. Cochrane Qualitative and Implementation Methods Group Guidance Series - paper 1: Introduction. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.09.025

Noyes, J., Booth, A., Flemming, K., Garside, R., Harden, A., Lewin, S., Pantoja, T., Hannes, K., Cargo, M., Thomas, J., 2017b. Cochrane Qualitative and Implementation Methods Group Guidance paper 2: Methods for assessing methodological limitations, data extraction and synthesis, and confidence in synthesized qualitative findings. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2017.06.020

Picot, J., Rose, M., Cooper, K., Pickett, K., Lord, J., Harris, P., Whyte, S., Böhning, D., Shepherd, J., 2017. Virtual chromoendoscopy for the real-time assessment of colorectal polyps in vivo: a systematic review and economic evaluation. Health Technology Assessment 21, 1–308. doi:10.3310/hta21790

Image of the Emergency Medicine Journal
       Pollard, D., Goodacre, S., Stevenson, M., Fuller, G., 2017. 10 Decision analysis modelling of diagnostic strategies for suspected pulmonary embolism in pregnancy: the DiPEP economic evaluation., in: Emergency Medical Journal. England, pp. A867–A868. doi:10.1136/emermed-2017-207308.10

       van Hoorn, R., Tummers, M., Booth, A., Gerhardus, A., Rehfuess, E., Hind, D., Bossuyt, P.M., Welch, V., Debray, T.P.A., Underwood, M., Cuijpers, P., Kraemer, H., van der Wilt, G.J., Kievit, W., 2017. The development of CHAMP: a checklist for the appraisal of moderators and predictors. BMC Medical Research Methodology 17, 173. doi:10.1186/s12874-017-0451-0

Wailoo, A., Hock, E.S., Stevenson, M., Martyn-St James, M., Rawdin, A., Simpson, E., Wong, R., Dracup, N., Scott, D.L., Young, A., 2017. The clinical effectiveness and Cost-Effectiveness of Treat-To-Target strategies in rheumatoid arthritis: A systematic review and cost-effectiveness analysis. Health Technology Assessment. (Rockv). 21, 1–258. doi:10.3310/hta21710

Thursday, 4 January 2018

New project: NICE topics

ScHARR-TAG has been allocated the following HST topics:
  • Volanesorsen for treating familial chylomicronaemia syndrome [ID1326] (Akcea Therapeutics)
  • Patisiran for treating hereditary transthyretin-related amyloidosis [ID1279] (Alnylam Pharmaceuticals)

Tuesday, 2 January 2018

Two new free online courses from HEDS

Image of white medicine tablets
CC BY 2.0 Janels Katlaps
HEDS will be running two popular FREE online courses again in 2018, so if you want to study with the experts at ScHARR to learn how difficult decisions are made about which treatments to fund, and how we can measure the value these treatments bring to patients and society, enrol now! Our Measuring and Valuing Health course is starting in February 2018 and our Health Technology Assessment course is starting in March 2018.
Click below to enrol:
Measuring and Valuing Health: https://www.futurelearn.com/courses/valuing-health
Health Technology Assessment: https://www.futurelearn.com/courses/hta

Thursday, 21 December 2017

Professor Eva Kaltenthaler receives ScHARR's Athena SWAN Award

Earlier this month HEDS Professor Eva Kaltenthaler attended the Athena SWAN Awards to accept ScHARR's second Silver Award. The event was hosted at the University of Glasgow.

Professor Kaltenthaler said: “This is a great achievement and underpins ScHARR's commitment to equality and diversity.”

Professor Eva Kaltenthaler receives ScHARR's Athena SWAN Award
Professor Eva Kaltenthaler receives ScHARR's Athena SWAN Award
The Athena SWAN Charter was established in 2005 to encourage and recognise commitment to advancing the careers of women in science, technology, engineering, maths and medicine (STEMM) employment in higher education and research.
In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles, and for trans staff and students. The charter now recognises work undertaken to address gender equality more broadly, and not just barriers to progression that affect women. 

More information on the Athena SWAN Award can be seen here